Christina Applegate Reveals Multiple Sclerosis Diagnosis in Twitter Post - Page 2 - Sitcoms Online Message Boards

TMC · 03-12-2024, 08:20 PM

Quote:

Known by pretty much everyone for guest starring as Rachel Green's sister in Friends, Christina Applegate is a cherished household face and name.

I'm shaking my head at this writer (Tom Earnshaw) for unironically suggesting that Christina is more known first and foremost, for playing Rachel's sister on Friends than for playing Kelly Bundy on Married...with Children.

TMC · 03-19-2024, 07:18 PM

Christina Applegate: I'm not interested in playing a character that shares my MS diagnosis

“I could not do that, it would be too sappy,” Applegate explained on the first episode of her and fellow MS sufferer Jamie-Lynn Sigler’s new podcast MeSsy, explaining what her life has been like since her diagnosis, according to The Daily Beast. “I physically just don’t feel good and I physically just don’t look like myself. I don’t know how to get out of this rut of self loathing and just giving up.”

TMC · 06-04-2024, 08:18 PM

Christina Applegate says she has "really fatalistic" depression amid MS battle

"I am in a depression right now, which I don't think I've felt for years," Applegate explained to Jamie-Lynn Sigler on the June 4 episode of their MeSsy podcast, which was recorded earlier this year, according to E! News. "Like a real, f*** it all, like real depression where it's kind of scaring me too a little bit because it feels really fatalistic."

TMC · 10-28-2025, 05:56 PM

Christina Applegate to reunite with her Married with Children castmates to raise money for Race to End MS

Applegate, who announced her MS diagnosis in 2021, will join Ed O’Neill, Katey Sagal and David Faustino at Los Angeles’ Wiltern Theatre on Wednesday, Jan. 28, 2026, for “An Evening with The Bundys: The Married with Children Cast Reunion” to celebrate and reminisce about their iconic 11-season Fox sitcom. Race to Erase MS, which is dedicated to the treatment and cure of Multiple Sclerosis, will receive $2 from every ticket sold. Attendees “can expect never-before-heard stories, rare behind-the-scenes moments, and plenty of laughs as the Bundys relive their most outrageous and iconic memories together,” but the reunion won’t be filmed.

TMC · 04-17-2026, 04:17 PM

Christina Applegate, 54, is 'hospitalized' amid MS battle... after revealing she is largely confined to her bed with the disease

According to reports, Christina Applegate, 54, has been hospitalized in LA since March 31. The actress was in the beginning of her press tour to promote her newly published memoir "You With The Sad Eyes" which was released a few weeks before the hospitalization. In the memoir, she talks openly about her courageous battle with MS, which was first diagnosed five years ago.

Applegate was also the cohost of the podcast 'MesSy', which she cohosted with actress Jamie-Lynn Singler, who went public with her own battle with MS in 2016. The podcast was 'paused' at the end of March, to allow Applegate to start her book press tour.

When questioned about her hospitalization, her rep said, “I have no comment on whether she is in the hospital or what her medical treatments are. She’s had a long history of complicated medical conditions that she has been refreshingly open about, as evidenced in her memoir and on her podcast.”

TMC · 04-18-2026, 06:55 PM

Quote:

Originally Posted by TMC

Christina Applegate, 54, is 'hospitalized' amid MS battle... after revealing she is largely confined to her bed with the disease

According to reports, Christina Applegate, 54, has been hospitalized in LA since March 31. The actress was in the beginning of her press tour to promote her newly published memoir "You With The Sad Eyes" which was released a few weeks before the hospitalization. In the memoir, she talks openly about her courageous battle with MS, which was first diagnosed five years ago.

Applegate was also the cohost of the podcast 'MesSy', which she cohosted with actress Jamie-Lynn Singler, who went public with her own battle with MS in 2016. The podcast was 'paused' at the end of March, to allow Applegate to start her book press tour.

When questioned about her hospitalization, her rep said, “I have no comment on whether she is in the hospital or what her medical treatments are. She’s had a long history of complicated medical conditions that she has been refreshingly open about, as evidenced in her memoir and on her podcast.”

Christina Applegate 'might not have a tomorrow': Friends reveal 'hellish' details of star's hospitalization amid MS battle... why they're crying at her bedside... and 'rough' reality of her decline

staytuned · 04-20-2026, 10:30 PM

I know she's got family and friends supporting her but why isn't she's given a recommended prescription in order to prevent the disease from spreading even further in her body, let alone have some recommended therapy exercises to help her out?

I don't know about you guys, but something tells me that her doctors from that hospital she's staying at aren't doing her any favors.

03-19-2024, 07:18 PM	#17
TMC Member Forum Idol Join Date: Jan 09, 2001 Posts: 124,545	Christina Applegate: I'm not interested in playing a character that shares my MS diagnosis “I could not do that, it would be too sappy,” Applegate explained on the first episode of her and fellow MS sufferer Jamie-Lynn Sigler’s new podcast MeSsy, explaining what her life has been like since her diagnosis, according to The Daily Beast. “I physically just don’t feel good and I physically just don’t look like myself. I don’t know how to get out of this rut of self loathing and just giving up.”

06-04-2024, 08:18 PM	#18
TMC Member Forum Idol Join Date: Jan 09, 2001 Posts: 124,545	Christina Applegate says she has "really fatalistic" depression amid MS battle "I am in a depression right now, which I don't think I've felt for years," Applegate explained to Jamie-Lynn Sigler on the June 4 episode of their MeSsy podcast, which was recorded earlier this year, according to E! News. "Like a real, f*** it all, like real depression where it's kind of scaring me too a little bit because it feels really fatalistic."

10-28-2025, 05:56 PM	#19
TMC Member Forum Idol Join Date: Jan 09, 2001 Posts: 124,545	Christina Applegate to reunite with her Married with Children castmates to raise money for Race to End MS Applegate, who announced her MS diagnosis in 2021, will join Ed O’Neill, Katey Sagal and David Faustino at Los Angeles’ Wiltern Theatre on Wednesday, Jan. 28, 2026, for “An Evening with The Bundys: The Married with Children Cast Reunion” to celebrate and reminisce about their iconic 11-season Fox sitcom. Race to Erase MS, which is dedicated to the treatment and cure of Multiple Sclerosis, will receive $2 from every ticket sold. Attendees “can expect never-before-heard stories, rare behind-the-scenes moments, and plenty of laughs as the Bundys relive their most outrageous and iconic memories together,” but the reunion won’t be filmed.

04-17-2026, 04:17 PM	#20
TMC Member Forum Idol Join Date: Jan 09, 2001 Posts: 124,545	Christina Applegate, 54, is 'hospitalized' amid MS battle... after revealing she is largely confined to her bed with the disease According to reports, Christina Applegate, 54, has been hospitalized in LA since March 31. The actress was in the beginning of her press tour to promote her newly published memoir "You With The Sad Eyes" which was released a few weeks before the hospitalization. In the memoir, she talks openly about her courageous battle with MS, which was first diagnosed five years ago. Applegate was also the cohost of the podcast 'MesSy', which she cohosted with actress Jamie-Lynn Singler, who went public with her own battle with MS in 2016. The podcast was 'paused' at the end of March, to allow Applegate to start her book press tour. When questioned about her hospitalization, her rep said, “I have no comment on whether she is in the hospital or what her medical treatments are. She’s had a long history of complicated medical conditions that she has been refreshingly open about, as evidenced in her memoir and on her podcast.”

04-20-2026, 10:30 PM	#22
staytuned Member Frequent Poster Join Date: Feb 22, 2025 Location: Some Where You are Posts: 268	I know she's got family and friends supporting her but why isn't she's given a recommended prescription in order to prevent the disease from spreading even further in her body, let alone have some recommended therapy exercises to help her out? I don't know about you guys, but something tells me that her doctors from that hospital she's staying at aren't doing her any favors.