From E! Online's "The Dotted Line":

Debra Messing lands a purr-fect role in Garfield. The Will & Grace star is ready to give voice to Garfield's girl in Fox's CGI meets live-action adaptation of the popular comic strip. Bill Murray provides the pipes of the lasagna-munching fat cat, with Breckin Meyer as his nebbish owner, Jon. Production is underway.

Good for her. She'll do great. She's got that cute voice. Bill Murray as Garfield is perfect casting.

awww...cute!
I can see her voice fitting right in!