1. The Jack Benny Program- 14 seasons and 235 episodes on CBS, 15/263 total
2. The Big Bang Theory- 12 seasons and 279 episodes
3. Two and a Half Men- 12 seasons and 262 episodes
4. The Danny Thomas Show- 11 seasons and 351 episodes
5. M*A*S*H- 11 seasons and 255 episodes
6. The Jeffersons- 11 seasons and 253 episodes
7. Murphy Brown (1988)- 10 seasons and 247 episodes
8. The Beverly Hillbillies- 9 seasons and 274 episodes
9. Everybody Loves Raymond- 9 seasons and 211 episodes
10. All in the Family- 9 seasons and 210 episodes
11. One Day at a Time (1975)- 9 seasons and 209 episodes
12. How I Met Your Mother- 9 seasons and 208 episodes
13. The King of Queens- 9 seasons and 207 episodes
14. Alice- 9 seasons and 202 episodes
15. I Love Lucy/The Lucy-Desi Comedy Hour- 9 seasons and 193 episodes
16. The George Burns and Gracie Allen Show- 8 seasons and 291 episodes
17. The Andy Griffith Show- 8 seasons and 249 episodes
18. Newhart- 8 seasons and 184 episodes
19. Mom- 8 seasons and 170 episodes
20. Petticoat Junction- 7 seasons and 222 episodes
21. My Three Sons- 7 seasons and 196 episodes on CBS, 12/380 total
22. The Mary Tyler Moore Show- 7 seasons and 168 episodes
23. Designing Women- 7 seasons and 163 episodes
24. Young Sheldon *- renewed through season 7, 105 episodes at the end of season 5
25. Rules of Engagement- 7 seasons and 100 episodes