I know that the Mad magazine spoof of The facts of life is posted here already, but I also found 2 other spoofs done on the show. They were from Cracked and Bananas magazine in the 80's. (Remember in the 70's, 80's when there were humor magazines: Mad, Cracked, Crazy, Sick, Bananas to name a few)
Here are the 3 spoofs all together so you can get a blast from the past.

https://www.facethefactspod.com/podblog/2019/6/6/the-yaks-of-life

https://www.facethefactspod.com/podblog/2019/6/6/the-factors-of-life

https://www.facethefactspod.com/podblog/2019/6/30/facts-of-life-goes-bananas

About 20 years ago, NBC had this sketch comedy series called The Rerun Show (https://en.wikipedia.org/wiki/The_Rerun_Show). It was sort of like an early variation of the Live in Front of a Studio Audience specials that Jimmy Kimmel and Norman Lear have put together for ABC. What I mean is that they would take recreate an episode from an old and classic sitcom with the original dialogue but with a completely new set of actors.

The only difference here, is that The Rerun Show intentionally twisted the original episode's subtext. With The Facts of Life, the episode that they spoofed was "Shoplifting".

https://i.ebayimg.com/images/g/SJ4AAOSwxYxU072N/s-l300.jpg

J0ow4GBK3As