8 Simple Rules - Amy Davidson (Kerry) is more than 6 years older than Kaley Cuoco (Bridget).

7th Heaven - Beverley Mitchell (Lucy) is over a year older than Jessica Biel (Mary).

Family Matters - Kellie Shanygne Williams (Laura) is several weeks older than Darius McCrary (Eddie).

Home Improvement - Jonathan Taylor Thomas (Randy) is a month older than Zachery Ty Bryan (Brad).

Others?

Malcolm In The Middle - Reese and Malcolm ( Frankie Muniz who played Malcolm is actually a year older than Justin Berfield who played Reese.)

Growing Pains= Tracey Gold Carol) is 16 months older than Kirk Cameron( Mike)

The Goldbergs = Troy Gentile ( Barry) is 3 months older than Hayley Orrantia ( Erica)

Blossom=Mayim Bialik( Blossom) is 4 months older than Joey Lawrence ( Joey)