https://screenrant.com/big-bang-theory-canceled-new-spinoff/

Despite The Big Bang Theory finally ending after 12 seasons, CBS can still capitalize on the sitcom's success by launching another spinoff.

Maybe a spin-off focusing on Howard and Bernadette and their family?

I think Stuart Bloom is the only character that would work in a spinoff. All the other characters are simply too iconic and tied to the original program. Stuart however is still not as major yet.

He'd have to move to another city though and in a completely different setting, of course.