This is another one that never reruns. It was of a lady in her 50's, maybe. She was adopted and trying to find her family in New York. She had a rare disease or something and needed a transplant from a bio family member. She had dark hair and spoke with a heavy NYC type accent. It was odd, because the address she wasn't given to find the hospital didn't exist...like they purposely didn't want her to know anything. The update they did have was her death :( I would like to view this episode, if possible. So if anyone knows her name or if their is a thread on this board, please direct me :)

http://unsolvedmysteries.wikia.com/wiki/The_Parents_of_Gayle_Samuels

Could this be the right case?

Here's the only other one I can think of, but not an adopted case. She was searching for her sister, who was also not a match, sadly. :(

http://unsolvedmysteries.wikia.com/wiki/Marilyn_Hahnlein

Yes, must have been the first. Thank you.