Would anyone watch a show if Will Smith made a TV Series after his movies Men In Black with a good plot it could be the most talked about Sci-FI show ever made.

https://www.youtube.com/watch?v=YjitYbdq2BE
https://www.youtube.com/watch?v=yIg9w4gLf_Q
https://www.youtube.com/watch?v=dBIXYPy5fBw

Even if both Will and Tommy Lee Jones themselves starred in it this would not be the most talked about Sci-Fi show ever made. That honor belongs to Star Trek.

I agree with Zoneboy- the entire Star Trek series and spinoffs definitely take the honor of most talked about sci-fi series ever made.
However, there was a "Men In Black" TV series made- but it was a cartoon series, not live action. If you're interested, the first season has been released to DVD (http://www.amazon.com/Men-Black-Animated-Series-Season/dp/B007ZEDZA6/ref=sr_1_7?ie=UTF8&qid=1366736597&sr=8-7&keywords=%22Men+in+Black%22+%2B+cartoon+series).
Will Smith and Tommy Lee Jones were not involved with it though. But it went for 4 seasons, back from 1997 to 2001, so it must have been pretty decent for those who like it. I just don't care much about the movies, TV series or the original comic books they were all based on myself though.

I woudent mind seeing a 6 part TV mini series of Men in Black with will and tommy lee jones instead of a 4th Men in Black film.

http://www.youtube.com/watch?v=RGJRkTIZAmQ