Jaleel would easily boost the ratings for the TV show The Big Bang Theory if he made a guest appearance as Steven Q Urkel aka Steve Urkel for just one episode, that would be a very entertaining episode to see him again after 15 long years.

https://www.youtube.com/watch?v=YjitYbdq2BE
https://www.youtube.com/watch?v=yIg9w4gLf_Q
https://www.youtube.com/watch?v=dBIXYPy5fBw

It would be hilarious to see the two of them debate their theories.

All jaleel white would have to do is shave his beard and he could pull it off being steve urkel since jaleel is 36 years old he should think about it if he wants his popularity back he once had back in the 90's, laura would be his wife by now in the year 2013 so they would both be on The Big Bang Theory as a married couple.

http://www.youtube.com/watch?v=RGJRkTIZAmQ

that would definitely be a jump-the-shark moment; i'd rather see them bring in Charlie Sheen as a still-alive Charlie Harper for a crossover, to bend the space-time continuum

that would definitely be a jump-the-shark moment; i'd rather see them bring in Charlie Sheen as a still-alive Charlie Harper for a crossover, to bend the space-time continuum
I agree, this would be totally jumping the shark.

With "The Big Bang Theory", it seems more likely that they might have Jaleel White guest star as himself rather than in the persona of Steve Urkel. It might be funny to see Sheldon and Steve Urkel in a battle of wits- and I could see Jaleel on there just as himself and explaining to Sheldon and his friends that he is very different from his Steve Urkel character- but honestly, White has already done similar scenarios in other venues (just see "Big Fat Liar" for proof), so I don't think he really needs it for his career. He has moved on from Family Matters and has done well with other projects.
And since both "Two and a Half Men" and "The Big Bang Theory" are both created by Chuck Lorre it seems likely that they could crossover- but I'd honestly rather not see it happen as I really don't care for the former show.

Perhaps they could kill Urkel off once and for all.. should have just gotten rid of that kid the first thing they did.

Jaleel White is never going to play Urkel again. It was a great role but he grew out of it. He'd look ridiculous now.

I no jaleel looks old now he's got wrinkles on his face but people said the same thing about mark paul and back in 2009 he shocked the world when he played zack morris on the jimmy fallen show lol

http://www.youtube.com/watch?v=82Aut0WrrhY