Besides Lori Loughlin, who was the hottest woman to ever appear/guest star on Full House (Candace Cameron and Andrea Barber as they got older don't count)? Off the top of my head, Nancy Valen as Rebecca's lamaze class teacher, that one cougar who wanted to see Jesse in small shower towel in that soap commercial, D.J.'s Spanish teacher that Danny fell for, and Erika Eleniak as Jesse's old high school flame.

Kristian Alfonso - in season 1 she appeared as Danny's co-worker who worked with him at the station. Jesse fell for her and used baby Michelle to get her attention.

Jennifer Nash, the young woman who took a liking to Danny...might've been season 5? IIRC, they went out to a grunge concert.

Nobody can touch Becky especially the last few seasons "goodness gracious" DJ got really cute too as well as That Rusty kids Mom.

Vanna White: "The Test"
Suzanne Somers: "Love on the Rocks"
Rhonda Shear: "Those Better Not be the Days"