This thread is for singers or bands that started in one genre and switched to another. This doesn't include crossover acts who had hits on more than one chart but remained within their own genre.

#1. The Oak Ridge Boys from gospel to country

Def Leppard - went from bluesy hard rock to straight-out commercial pop music

Conway Twitty - from rock to country

The Temptations went from basic R&B in the late 60s to psychedelia - concurrent with the change in lead singers (David Ruffin to Dennis Edwards) and writers/producers (Smokey Robinson to Norman Whitfield).

The Bee Gee's went from lite rock in the 60s to disco in the mid to late 70s.

Charlie Rich - from rock to country

Ministry --went from 80's synth-pop to industrial metal.

Rihanna went from Caribbean/R&B style music to mainstream dance pop.

Darius Rucker went from lead singer in the alternative band Hootie and the Blowfish to being a single country singer.

Darius Rucker went from lead singer in the alternative band Hootie and the Blowfish to being a single country singer.

You had some good ones but it's one per non-consecutive turn so feel free to add another after someone else posts.

The Beatles, from romantic/dance pop to avant garde musings complete with Indian influences.

Pantera went from standard 80's glam/pop-metal to a heavier, edgier sound called power groove in the early 90's which incorporated thrash, hardcore, and a splash of Southern rock. They changed completely from anything they were before.

They invented the 90's on 'Cowboys From Hell'. Before Seattle.

Exile - from pop to country