Rob and Laura Petrie - The Dick Van Dyke Show
Steven and Elyse Keaton - Family Ties
John and Olivia Walton - The Waltons
Bob and Emily Hartley - The Bob Newhart Show

Niles and Daphne Crane-Frasier
Jason and Maggie Seaver-Growing Pains
Jesse and Rebecca Katsopolis-Full House
Cliff and Clair Huxtable-The Cosby Show
Phil and Vivian Banks (Janet Hubert)-The Fresh Prince of Bel-Air
Charles and Caroline Ingalls-Little House on the Prairie
George and Louise Jefferson-The Jeffersons
George and Marsha Owens-Mr. Belvedere
Dan and Roseanne Conner-Roseanne
Eric and Annie Camden-7th Heaven
Tony and Jeannie Nelson-I Dream of Jeannie
Byron Sully and Dr. Michaela Quinn-Dr. Quinn Medicine Woman
Darrin and Samantha Stephens-Bewitched

Jonathan and Jennifer Hart--Hart To Hart :happyface
Howard and Marion Cunningham--Happy Days

Donna and Alex Stone-'The Donna Reed Show'
Mike and Carol Brady- 'The Brady Bunch'
Charles and Caroline Ingalls- 'Little House on the Prairie'
Ray and Debra Barone-'Everybody Loves Raymond'

Ward and June Cleaver - Leave It To Beaver
Martin and Natalie Lane - The Patty Duke Show

Dick Van Dyke and Mary Tyler Moore (The Dick Van Dyke Show)
Paul Reiser and Helen Hunt (Mad About You)
Kyle Chandler and Connie Britton (Friday Night Lights)

John Astin and the late Carolyn Jones were great as Gomez and Morticia Addams on ABC's "The Addams Family".

Harold and Jean Weir (Freaks and Geeks)
Zeke and Camille Bravermam (Parenthood)
Walter and Skyler White (Breaking Bad)
Frank and Marie Barone (Everybody Loves Raymond)
Phil and Claire Dunphy (Modern Family)
Mitchell Pritchett and Cameron Tucker (Modern Family)
Jack and Norma Arnold (The Wonder Years)

aliceand Ralph Kramden in the hooney mooners
allen and amy Matthews on boy meet world

Basil and Sybil Fawlty

How about the most underrated sitcom married couple ever, Doug and Carrie from King of Queens.

Mary and Lester from 227
Marsha and George from Mr. Belvedere
Daisy and Onslow from Keeping Up Appearances

I see a lot of repeats on here, but there are a lot of good ones I hadn't even thought of that weren't on my list.

I would like to add one more.

Carl and Harriette Winslow-Family Matters