With a slew of daytime syndicated talk show projects jockeying for a fall 2012 berth, a big one is entering the fray for fall 2013. Queen Latifah is set to host a new daytime talk show that Flavor Unit, her company with Shakim Compere, will co-produce with Will Smith and James Lassiter’s Overbrook Entertainment and Sony Pictures Television. Compere and Overbrook’s Miguel Melendez, who were instrumental in getting the project together, will serve as executive producers with Queen Latifah and Overbrook’s Lassiter, Will Smith and Jada Pinkett Smith.

http://www.deadline.com/tv/

I know for a fact that Queen Latifah already had her chance at a nationally syndicated talk show, which ran from 1999-01 (where I lived at that time, it aired on the FOX affiliate at 2:00 PM).

^I was just about to say that. My then UPN affiliate aired it around 4-ish in the afternoon.