I was just watching the season 2 DVD set of Lois & Clark and there's a mini-Knots reunion in the episode "That Old Gang Of Mine."

Joseph Gian played Clyde Barrow, John Pleshette played Dr. Emil Hamilton and William Devane played Al Capone. It was a fun episode, with Devane chewing the scenery as Al Capone, transplanted from the thirties into the nineties.

Lois & Clark shared some of the same producers/behind-the-scenes people as Knots, so the connection is there. It's a fun episode.