View Full Version : Favorite TV friendships


browneyes106
08-20-2009, 12:18 AM
Friends-All the friendships
The Nanny-Fran and Val
Dawson's Creek-Dawson and Joey
The Wonder Years-Kevin and Paul

Marvo301
08-20-2009, 12:31 AM
Laverne and Shirley - Laverne and Shirley
Lenny and Squiggy - Laverne and Shirley
Fonzie and Ritchie - Happy Days
Larry and Balki - Perfect Strangers
Lucy and Ethel - I Love Lucy
Lucy and Viv - The Lucy Show
Ralph and Ed - The Honeymooners
Buddy and Sally - The Dick Van Dyke Show
Charles and Buddy - Charles in Charge
Raj, Rerun, and Dwayne - What's Happening!
Hawkeye and Trapper - M*A*S*H
Hawkeye and B.J. - M*A*S*H

Scoobiedoo30
08-20-2009, 12:45 AM
Sanford and Son Lamont and Rollo

Marvo301
08-20-2009, 12:53 AM
Ralph and Potsie - Happy Days
Wally and Eddie - Leave it to Beaver

comedyfreak
08-20-2009, 04:26 AM
Friends-All the Friends gang, great ensamble .
Happy Days-Ritchie, Ralpn, and Potsie.
Welcome Back Kotter-Vinnie, Freddy, Juan, and Horshack.
Leave It To Beaver-Wally and Eddie & Beaver and Larry Mondello
Bewitched-Samantha and Louise
Frasier-Frasier and Roz
I Love Lucy-Lucy and Ethel
The Honeymooners-Ralph and Ed
The Flintstones-Fred and Barney
What's Happening-Raj, Dwayne, and Rerun

janet42
08-20-2009, 04:33 AM
Petticoat Junction: Same Drunker and Kate Bradley
Petticoat Junction: Charlie Pratt and Floyd Smoot
Emergency: John Gage and Roy Desoto
Facts of Life: Tootie and Natalie
George Burns and Gracie Allen Show: Gracie Allen and Blanche Morton
Three's Company: Janet Wood and Chrissy Snow & Janet Wood and Terri Barnes

dawsongirl
08-20-2009, 10:52 AM
Magnum, TC, and Rick - Magnum, PI
Lucy and Ethel - ILL
Pete and Jim - Adam-12
Gage and Desoto - Emergency
Fry and Bender - Futurama
Tony and Roger - I Dream of Jeannie

McGillicuddy
08-20-2009, 11:24 AM
Laverne and Shirley - Laverne and Shirley
Lenny and Squiggy - Laverne and Shirley
Fonzie and Ritchie - Happy Days
Larry and Balki - Perfect Strangers
Lucy and Ethel - I Love Lucy
Lucy and Viv - The Lucy Show
Ralph and Ed - The Honeymooners
Buddy and Sally - The Dick Van Dyke Show
Charles and Buddy - Charles in Charge
Raj, Rerun, and Dwayne - What's Happening!
Hawkeye and Trapper - M*A*S*H
Hawkeye and B.J. - M*A*S*H
Mary and Rhoda - Mary Tyler Moore Show
Dorothy, Blanche and Rose - The Golden Girls

Heidi Dawn
08-20-2009, 11:37 AM
Happy Days:
Richie & Fonzie
Ralph & Potsie
Joanie & Jenny

Laverne & Shirley

Full House:
D.J. & Kimmy
Danny & Joey

Mash:
Hawkeye & Trapper
Hawkeye & B.J.

dakert
08-20-2009, 12:17 PM
And the Ultimate TV Friendship is:

Tod and Buzz of Route 66

If you havent seen Route 66 you are missing out on some excellent tv entertainment.

Sharop
08-20-2009, 12:20 PM
Frasier - Frasier and Niles (okay, they're brothers, but they were friends as well.)

Cheers - Sam and Frasier, Sam and Rebecca, Norm and Cliff

Family Ties - Alex and Skippy

The Wonder Years - Kevin and Paul

Strange Days at Blake Holsey High - Josie and Lucas, Lucas and Marshall, Lucas and Vaughn.

Gemini_89
08-20-2009, 01:45 PM
1. Samuel "Screech" Powers & Zack Morris- Saved By The Bell: Here you have two people who have no business being friends except for the fact that Zack uses Screech to copy his homework and Screech uses him to be part of the cool kids. So, on the surface it seems like they're not really friends. They're just using each other. But many times it was shown that they did in fact care for each other.

The best Zack-Screech episodes are:

Love Letters (from "Miss Bliss")
The Gift
Screech's Woman
Miss Bayside
Close Encounters of the Nerd Kind
Screech's Birthday

If those episodes don't prove that the Zack-Screech friendship worked best then I don't know what does.

2. Lisa Turtle & Zack Morris- Saved By The Bell: I loved their friendship because it went deeper and beyond of what you might expect. You could "feel" the chemistry in the episode "Operation Zack". When they were reminicing on their childhood the night before his surgery, it was so cute. I loved it that Lisa was there for him (twice) when Zack was at his scariest moment of his life. It was fate that Lisa just so happens to get a part-time candy striper job right before Zack injured his knee! Nobody else could have soothed his worries and nerves like Lisa could, (given on their history). When Lisa were finishing his sentences, placing her hand on top of his, and at the end, that tender moment right before the surgery, Zack reached his hand out and Lisa took it and held it, so beautiful! aww. They had the "we are friends but we wish that we were more" vibe. I loved how Lisa gave him a kiss, ran her fingers through his hair, and said a prayer for him, "Please God, take care of my friend." Sounds like a scene straight from a soap opera or somethin! lol, if that scene didn't deserve an Emmy Nod, than i don't know what the hell did!.

Remember the "Fake I.D.s" episode when Zack & Lisa was at the nght club? It was a brief moment but while they were talking, Zack reached out and brushed/touched Lisa's breast! Unintentional? (I had to re-watch the episode again to make sure if i was seeing clearly), teehee.........

And don't forget about the "Lisa's Card" episode when Zack was the first one who went out of his way to help Lisa pay off her father's credit card that she ran up. Out of all of the cast members, you can feel that he genuinely wanted to help Lisa the most, it was so real, the intentions, so SINCERE!

I can feel the chemistry between the two in this eppy:

-When they were under the desk together for that annual earthquake drill

-When Lisa grabbed Zack's hand, holding it, and thanking him for everything that he has done. He grabbed hers back, that part of the scene ended there before commercial break, the look on both of their faces were PRICELESS, the connection, you can tell that they started seeing each other when they made that episode, '89.

In the "Mystery Weekend" episode when Zack & Lisa was in the room alone together, they hugged, it was a brief moment, but i liked it none-the-less!.

3. Jessie Spano & Zack Morris- They been best friends since they were lil bitty kids. Zack was the only guy who she let climb through her window! lol. The scene when she breaks down and Zack's showing his strength by being there for her in the "Jessie's Song" episode was classic!

4. Olivia Benson & Stabler-Law & Order: SVU: Great chemistry

MickeyMac
08-20-2009, 04:45 PM
Lucy & Ethel from I Love Lucy
Fred and Barney and Wilma and Betty from the Flintstones
Major Nelson and Major Healey from I Dream of Jeannie
Samantha and Louise from Bewitched
Illya Kuryakin and Napoleon Solo from The Man From UNCLE
Crockett and Tubbs from Miami Vice
Eddie, Wally and Lumpy from Leave It To Beaver
Magnum, Rick and TC from Magnum PI
Kelly Robinson and Alexander Scott from I Spy
Todd and Buzz from Route 66

tv star collector
08-20-2009, 06:50 PM
Andy Taylor and Barney Fife (The Andy Griffith Show)
Bruce Wayne and Dick Grayson (Batman)
Brandon Walsh and Steve Sanders (Beverly Hills 90210)
Brandon Walsh and Andrea Zuckerman (Beverly Hills 90210)
Sheldon, Leonard, Howard and Raj (The Big Bang Theory)
B.J. McCay and Bear the chimp (BJ and the Bear)
Rocky and Bullwinkle (The Bullwinkle Show)
Gunther Toody and Francis Muldoon (Car 54, Where Are You?)
Ed Brown and Chico Rodriguez (Chico and the Man)
Cisco and Pancho (The Cisco Kid)
Daniel Boone and Mingo (Daniel Boone)
John Gage and Roy DeSoto (Emergency!)
Fred Flintstone and Barney Rubble (The Flintstones)
Gilligan and the Skipper (Gilligan's Island)
Marshal Dillon and Chester Goode (Gunsmoke)
Richie Cunningham and Arthur "Fonzie" Fonzarelli (Happy Days)
Hercules and Iolaus (Hercules: The Legendary Journeys)
Jonathan Smith and Mark Gordon (Highway to Heaven)
Ralph Kramden and Ed Norton (The Honeymooners)
Howdy Doody and Buffalo Bob Smith (Howdy Doody)
Tony Nelson and Roger Healy (I Dream of Jeannie)
Lucy Ricardo and Ethel Mertz (I Love Lucy)
Kelly Robinson and Alexander Scott (I Spy)
Denny David and Steve Connors (It's a Great Life)
Hank Hill, Boomhauer, Dale Gribble and Bill Dauterive (King of the Hill)
Michael Knight and KITT (Knight Rider)
Kukla, Fran and Ollie (Kukla, Fran & Ollie)
Timmy and Lassie (Lassie)
Laverne DeFazio and Shirley Feeney (Laverne & Shirley)
Lenny and Squiggy (Laverne & Shirley)
Chester Riley and Jim Gillis (The Life of Riley)
Charles Ingalls and Jonathan Garvey (Little House on the Prairie)
The Lone Ranger and Tonto (The Lone Ranger)
Napoleon Solo and Illya Kuryakin (The Man from U.N.C.L.E.)
Wilbur Post and Mister Ed (Mister Ed)
Robinson Peepers and Harvey Weskit (Mr. Peepers)
Micky, Davy, Mike and Peter (The Monkees)
Kermit and Fozzie (The Muppet Show)
Tim O'Hara and Uncle Martin (My Favorite Martian)
Huck Finn, Tom Sawyer and Becky Thatcher (New Advs. of Huck Finn)
Moe, Larry and Curly-Joe (The New Three Stooges)
Paul Winchell and Jerry Mahoney (various shows)
Larry and Balki (Perfect Strangers)
Sgt. Bilko and Pvt. Doberman (The Phil Silvers Show)
Popeye and Wimpy (Popeye)
Quick Draw McGraw and Baba Looey (Quick Draw McGraw)
Amos McCoy and George MacMichael (The Real McCoys)
Rusty and Rin Tin Tin (Rin Tin Tin)
Max and Michael (Roswell)
Liz and Maria (Roswell)
Ruff and Reddy (Ruff & Reddy)
Zack Morris and Lisa Turtle (Saved by the Bell)
Shaggy and Scooby-Doo (Scooby-Doo)
Clark Kent and Chloe Sullivan (Smallville)
Captain Kirk and Mr. Spock (Star Trek)
Jake Cutter, Corky and Jack (Tales of the Gold Monkey)
Tennessee Tuxedo and Chumley (Tennessee Tuxedo & His Tales)
Monica, Tess and Andrew (Touched by an Angel)
The Virginian and Trampas (The Virginian)
Wild Bill Hickok and Jingles (Wild Bill Hickok)
Xena and Gabrielle (Xena, Warrior Princess)
Fox Mulder and Dana Scully (The X-Files)
Yogi Bear and Boo Boo (The Yogi Bear Show)

BewitchingGirl
08-20-2009, 07:40 PM
Starsky and Hutch

Gemini_89
08-20-2009, 10:00 PM
Zack Morris and Lisa Turtle (Saved by the Bell)

awesome!! i'm glad someone else feels the same way i do.

*Pleasant Tomorrow*
08-20-2009, 10:06 PM
All of the friendships on Three's Company
Will and Grace and Jack and Karen on Will and Grace
Lucy and Ethel on I Love Lucy
Laverne and Shirley on Laverne and Shirley
The cast of Friends

DSfan
08-20-2009, 10:12 PM
I would have to say Cory and Shawn from Boy Meets World.

Jack Gomez
08-20-2009, 11:23 PM
All of the friendships on Three's Company


I agree. :)

Some of my other favorites:

All the friendships from - Freaks and Geeks
Jean-Luc Picard and Beverly Crusher - Star Trek: The Next Generation
Kirk, Spock and McCoy - Star Trek
Mulder and Scully - The X-Files
Kaylee and Simon - Firefly
Shane Vansen and Cooper Hawkes - Space: Above and Beyond
Buffy, Willow and Xander - Buffy the Vampire Slayer
Dennis and Tommy - Dennis the Menace
Martin, Tommy and Cole - Martin
Pam and Gina - Martin
Parker, Mikey and Jerry - Parker Lewis Can't Lose
Snoopy and Woodstock - Peanuts specials
Charlie Brown and Linus - Peanuts specials
Peppermint Patty and Marcie - Peanuts specials
Spider-Man, Iceman and Firestar - Spider-Man and His Amazing Friends

Chocoholic
08-20-2009, 11:32 PM
Norm and Cliff (Cheers)
JD and Turk (Scrubs)
Hawkeye and Trapper (MASH)
Bart and Milhouse (The Simpsons)
The whole gang on Wings

catlover79
08-21-2009, 12:53 AM
Mary & Rhoda
Larry & Balki
The Ricardos & Mertzes
Kermit & Fozzie
Wally, Eddie & Lumpy
The Duke cousins (OK, they and Uncle Jesse were family, but very tight).

Schmoopie
08-21-2009, 04:20 AM
Beaver and Larry-Leave it to Beaver
Beaver and Whitey-Leave it to Beaver
Eddie and Wally-Leve it to Beaver
Lumpy and Wally-Leave it to Beaver
Kimmy and DJ-Full House
Jessie and Joey-Full House
Jerry and Kramer_Seinfeld
Jerry and Elaine-Seinfeld
Jerry and George-Seinfeld
Richie and Fonzie-Happy Days
Adrian and Sharona-Monk
Adrian and Dr. Kroger-Monk
Adrian and Natalie-Monk
Adrian and Leland-Monk
Natalie and Ambrose-Monk
Bert and Ernie-Sesame Street
Big Bird and Snuffleupagus-Sesame Street
Charlie Brown and Linus-Peanuts
Peppermint Patty and Charlie Brown-Peanuts
Peppermint Patty and Marcie-Peanuts
Snoopy and Woodstock-Peanuts
Brandon and Dylan-Beverly Hills 90210 (original)

Gemini_89
08-21-2009, 04:42 AM
JD and Turk (Scrubs)

How can i forget Scrubs!?! i love that pairing too, that was the epitome of a beautiful bromance

I also liked Carla & Elliot's relationship from Scrubs: They started out not liking each other but it eventually turned into a lovely friendship.
Dr. Cox & Carla-Scrubs

Tommy & Chucky-Rugrats

The whole Recess gang

comedyfreak
08-21-2009, 08:27 AM
Malcolm and Stevie-Malcolm In The Middle
Ted Mosby -How I Met your Mother
Marshall Eriksen -How I Met Your Mother
Robin Scherbatsky -How I Met Your Mother
Barney Stinson -How I Met Your Mother
Lily Aldrin -How I Met Your Mother
Roseanne and Crystal-Roseanne
Miley, Lily, and Oliver-Hannah Montana
Carly, Sam, and Freddy-iCarly
Mike and Boner-Growing Pains
Alex and Skippy-Family Ties
Eddie and Waldo Geraldo Faldo-Family Matters
Blossom and Six-Blossom
Kip and Henry-Bosom Buddies

catlover79
08-21-2009, 08:49 AM
Beaver and Larry-Leave it to Beaver
Beaver and Whitey-Leave it to Beaver
Eddie and Wally-Leve it to Beaver
Lumpy and Wally-Leave it to Beaver
Kimmy and DJ-Full House
Jessie and Joey-Full House
Jerry and Kramer_Seinfeld
Jerry and Elaine-Seinfeld
Jerry and George-Seinfeld
Richie and Fonzie-Happy Days
Adrian and Sharona-Monk
Adrian and Dr. Kroger-Monk
Adrian and Natalie-Monk
Adrian and Leland-Monk
Natalie and Ambrose-Monk
Bert and Ernie-Sesame Street
Big Bird and Snuffleupagus-Sesame Street
Charlie Brown and Linus-Peanuts
Peppermint Patty and Charlie Brown-Peanuts
Peppermint Patty and Marcie-Peanuts
Snoopy and Woodstock-Peanuts
Brandon and Dylan-Beverly Hills 90210 (original)
How could I have forgotten Bert & Ernie? They were the Felix Unger & Oscar Madison of Sesame Street!! :cool:

Gemini_89
08-21-2009, 10:38 AM
Raven, Chelsea, and Eddie-That's So Raven
Lizzie, Miranda, Gordon-Lizzie Mcquire
Moesha, Hakeem-Moesha

dawsongirl
08-21-2009, 03:02 PM
And the Ultimate TV Friendship is:

Tod and Buzz of Route 66

If you havent seen Route 66 you are missing out on some excellent tv entertainment.
Gah! Forgot that one. Yes, they're awesome.

dawsongirl
08-21-2009, 03:04 PM
Magnum, TC, and Rick - Magnum, PI
Lucy and Ethel - ILL
Pete and Jim - Adam-12
Gage and Desoto - Emergency
Fry and Bender - Futurama
Tony and Roger - I Dream of Jeannie
Geez...forgot Felix and Oscar too. I'm not doing so good here! lol

Zebra 3
08-21-2009, 09:11 PM
What she said...

Starsky and Hutch

Gemini_89
08-22-2009, 11:31 PM
How the hell could i forget Lisa Turtle's & Screech's friendship from Saved By The Bell????? Even though Lisa was SEEMINGLY annoyed by Screech's unrelenting pursuit for her, she grew into appreciating that and ultimatally, started developing feelings for him!

I. e. In that one episode, Screech and Lisa had a date to go to the movies. She actually enjoyed herself, and was all set to go to prom with Screech.

In the "Senior Prom" episode, describing his good qualities then taking him to the Senior Prom, she even gave him a kiss!

Remember in the "Bayside Triangle" episode when Screech gave Lisa that necklace/locket with a picture of himself in it? That NEXT day, she was wearing it! At the end of the episode when Screech said that he wouldn't forget her, (as she was holding his necklace which was still around her neck) she looked straight into his eyes and said that she wouldn't forget him! THE WAY that she said it it sounded really loving/romantic in a Soapy sort of way.

In the "Graduation" episode she defended Screech against Jessie who dissed him in a disrespectful manner. She also defended him against some other bitch in the "Senior Prom" episode.

In Conclusion: Yes he annoyed her to no wits end but at the end of the day, she always had Screech's best interest at heart.

Chocoholic
08-22-2009, 11:44 PM
I can't believe I forgot Bert and Ernie!

Gemini_89
08-23-2009, 04:58 PM
'Slaps forehead', Dr. Cox & J.D. from Scrubs.

Reverend Jim
08-23-2009, 05:49 PM
http://farm3.static.flickr.com/2550/3849416147_71d6a44590_o.jpgMy favorite television friendship was the one between Felix Unger (Tony Randall) and Oscar Madison (Jack Klugman) on "The Odd Couple".

ryan423
08-23-2009, 09:39 PM
Cory and Shawn - Boy Meets World
Barney Stinson and his Ego (LOL) - How I Met Your Mother
Reba and Barbra Jean - Reba
Wilson and House - House M.D.
Matt and Danny - Studio 60 on the Sunset Strip

Gemini_89
08-26-2009, 09:00 AM
I liked Tori Scott's & Lisa's Turtle's friendship on Saved By The Bell. Tori had better chemistry all around with Lisa than she ever had with Zack! That's why i had a "wtf moment" when they paired Tori up with Zack. What were the producers/writers thinkin????? They had ZERO chemistry plus Tori LIKED Lisa more! i.e. the way she would look at her whenever she walks into a room, or started talking, amongst other things.

As far as Lisa's sexuality, who knows? She definitely doesn't give off the Lesbian vibe to me. Maybe that'll explain the reason why Lisa never had a steady boyfriend, (makes me wonder). I know she and Tori became really close friends. They always hung out and did things together, it doesn't seem like that they would have much in common, (but i could be wrong) what the heck would they talk about? What would they REALLY do in their alone time with each other? (i wonder what else happened that night when they were staying up late workin on the "Fall decorations for the Party" hmm.........)

Anyway, i think that they could have made a cute couple, but of course that subject ALONE would have been too controversial and intense for the show.......

Gemini_89
08-27-2009, 05:36 PM
Screech, Lisa, and Zack's relationship from Saved By The Bell was special because they knew each other longer than the other cast members who just tagged along. They were the ORIGINAL kids on Good Morning Miss Bliss: Pre-Bayside Days. In one of the episodes, Lisa & Zack were reminiscing about the time all 3 of them, Zack, Lisa, and Screech went ice-skating. I loved their bond together. The three Musketeers!

mstewart
08-28-2009, 12:55 AM
Laura Petrie and Millie Helper of the Dick Van Dyke Show. That was an underrated friendship should had been more explored and storylines given more to them. The chemistry between Mary Tyler Moore and Ann Guilbert Morgan was outstanding and they did some of the classic moments of the Dick Van Dyke Show.

catlover79
08-28-2009, 12:10 PM
How about Harris & Dietrich from Barney Miller and Jo & Blair from Facts of Life? I call them the reluctant best friends because even though they drove each other up the wall, they still understood each other better than anyone else. :D

Rosslover
08-28-2009, 10:32 PM
the "Sex " girls ...Carrie Samantha Charlotte and Miranda
Stanford and Carrie ...SOTC
Cybill and Mary Ann ...partners in crime to eliminate the world of the "evil" DR DICK.
of course the six FRIENDS they laughed and LOVED together...
Karen and her poodle and Grace and Will..W and G
Hawkeye and Margaret ...MASH
Maddie and David ...Moonlighting
the boys of Entourage...Vince , E , Turtle and Drama

McGillicuddy
08-28-2009, 10:35 PM
Karen and her poodle


Karen and her poodle!!!:lol: :lol: :lol:

70s show watcher
08-29-2009, 12:29 AM
And the Ultimate TV Friendship is:

Tod and Buzz of Route 66

If you havent seen Route 66 you are missing out on some excellent tv entertainment.i agree i havent seen too many eps but the one ive seen are great

macro_grp02
08-29-2009, 10:38 AM
Who could forget Friends? But i also watched Joey on his own. He was really funny. It was a pity it was cancelled. Also the guys in Will and Grace are great. :)

browneyes106
08-29-2009, 01:07 PM
I also loved Karen and Jack's friendship in Will and Grace

biffbronson
09-02-2009, 06:53 AM
Friendship of Chip Douglas and Ernie Thompson, with Ernie later becoming his brother by adoption ~~ on My Three Sons.

Will and Grace Fanatic
09-02-2009, 08:58 PM
Will and Grace from Will and Grace
Jack and Karen from Will and Grace
Lucy and Ethel from I Love Lucy
tim and Al from Home Improvement

James
09-06-2009, 07:17 PM
The Wonder Years - Kevin and Paul

Michelle, I agree, although it wouldn't be complete without Winnie!

Oh, and I echo the feelings of those who nominated Laverne and Shirley, as well as Larry and Balki.

comedyfreak
09-10-2009, 05:01 AM
Edith Bunker and Louise Jefferson-All In The Family

Scoobiedoo30
09-10-2009, 12:20 PM
now that was a great friendship edith and Louise Jeffersons

Fallon97
05-24-2010, 05:50 PM
Charlie's Angels: Kelly, Kris, Sabrina, Bosley, and Jill.

Friday the 13th: The Series: Micki, Ryan, and Jack.

Xena: Xena, Gabrielle, and Joxer.

I Dream of Jeannie: Jeannie, Major Nelson, and Major Healey.

Martin: Martin/Tommy/Cole.......and Pam/Gina.

Living Single: Khadijha, Regine, Maxine, and Sinclair.

The Golden Girls: Blanche, Rose, Dorothy, and Sophia.

Three's Company: Janet, Jack, Krissy, Terri, Cindy, Larry, The Ropers, and Mr. Furley.

Laverne and Shirley: Laverne and Shirley.

Starsky and Hutch: Starsky, Hutch, and Huggybear.

Buffy the Vampire Slayer: Willow, Buffy, Zander and Giles.

Dallas: Pam and Sue Ellen.

Sanford and Son: Lamont/Rollo...........Fred/Grady/Bubba.

Good Times: Wilona and Florida.

The Jeffersons: Louise/Florence/Helen

*Pleasant Tomorrow*
05-24-2010, 05:53 PM
I'm going to add in Liz Lemon and Jack Donaghy from 30 Rock.

catlover79
05-24-2010, 06:51 PM
Too many to pick!!! :D

Mrgman
05-29-2010, 09:59 PM
Turk and jd from scrubs

Kristen
05-29-2010, 10:21 PM
OK, off the top of my head:

Roz and Frasier (Frasier)
Niles and Frasier (Yeah, they're brothers, so what? LOL)
Joe, Brian and Helen (Wings)
Mary and Rhoda (The Mary Tyler Moore Show)
Norm and Cliff (Cheers)
Rose, Blanche, Dorothy and Sophia (Golden Girls)
Julia, Suzanne, Mary Jo, and Charlie (Designing Women - Yeah, Julia and Suzanne are sisters, but it still counts.)

- Kristen