Sources said it was unclear whether Raimi, Tobey Maguire and Kirsten Dunst will be back. If they aren't, Vanderbilt's script would be the blueprint for a franchise reboot. After committing to his fourth "Spider-Man" film, Raimi signed on to direct a new franchise based on the massively multiplayer role-playing online computer game "World of Warcraft" for Legendary Pictures and Warner Bros. Maguire and Dunst were locked into the first three pictures and made a new deal for "Spider-Man 4." It's unclear how long they want to continue with the series.

http://www.variety.com/article/VR1118007333.html?categoryid=10&cs=1

I just read that Sony has commissioned scripts for 5 and 6 and they don't even had a finalized one for 4 yet!

http://www.denofgeek.com/movies/304116/sony_commissions_spiderman_5_and_spiderman_6_scripts.html

They better go back to the roots of 1 and 2 or this franchise is in trouble; and keep the original stars while they are at it!