In sort of an odd casting for a different studio and different network, Ausiello is reporting that Kaley Cuoco will appear in the season finale for Grey's Anatomy on May 14. See here :

http://ausiellofiles.ew.com/2009/04/greys-exclusi-1.html

That'll be interesting to see

I'll definitely have to check that out, my mom is a huge Greys fan so I'll have to get her to remind me when the finale airs :lol:. T4P!

I know she can do funny and she played serious during the eps on 8 Simple Rules dealing with John's death, but other than that this will be my first time seeing her do dramatic stuff. I think she will be just as good. I've also seen clips of her when she was in Fat Like Me on Lifetime. I think she'll pull of Grey's if she can pull off that.