You can do as many as you like. I'm doing one for each decade, but you can do it any way you like.

1. 1950s
Mondays - The Life of Riley
Tuesdays - I Love Lucy
Wednesdays - The Adventures of Ozzie and Harriet
Thursdays - The Honeymooners
Fridays - Make Room for Daddy

2. 1960s
Mondays - The Many Loves of Dobie Gillis
Tuesdays - The Donna Reed Show
Wednesdays - Bewitched
Thursdays - My Three Sons
Fridays - F Troop

3. 1970s
Mondays - M*A*S*H
Tuesdays - Taxi
Wednesdays - Chico and the Man
Thursdays - The Odd Couple
Fridays - Happy Days

4. 1980s
Mondays - ALF
Tuesdays - Charles in Charge
Wednesdays - Night Court
Thursdays - Cheers
Fridays - Perfect Strangers

5. 1990s
Mondays - Hey Dude
Tuesdays - NewsRadio
Wednesdays - Ellen
Thursdays - Wings
Fridays - Boy Meets World

6. 2000s
Mondays - The King of Queens
Tuesdays - Less Than Perfect
Wednesdays - That '70s Show
Thursdays - 8 Simple Rules
Fridays - Phil of the Future

I think I'll follow your decade lead

1950s
Make Room for Daddy Mondays
Lucy Tuesdays
Ozzie & Harriet Wednesdays
Beaver Thursdays
Father Knows Best Fridays

1960s
Mayberry Mondays (Andy Griffith Show)
Dick Van Dyke Tuesdays
Bewitched Be-Wednesdays
Jeannie Thursdays
Smart Fridays (Get Smart)

1970s
Mary Mondays
Rhoda Tuesdays
Newhart Wednesdays
M*A*S*H Thursdays
Fonzie Fridays

1980s
Cosby Mondays
Cheers Tuesdays
Newhart Wednesdays
Roseanne Thursdays (I know it was more of a 90s show, but I like the 80s episodes better)
Wonder Years Fridays (same with this one)

1990s
Mad About You Mondays
Seinfeld Tuesdays
Wings Wednesdays
Raymond Thursdays
Friends Fridays

2000s
Office Mondays
8 Simple Rules Tuesdays
Men Wednesdays (Two and a Half Men)
American Dreams Thursdays (I know it's an hour show, but who cares)
Jim Fridays (According to Jim)

1980's:
One Day At A Time Mondays
The Facts Of Life Tuesdays
Gimme A Break Wednesdays
A different World Thursdays
Murphy Brown Fridays
Moonlighting Saturdays
Murder, She Wrote Sundays

1990's:
Will and Grace mondays
Friends Tuesdays
Designing Women Wednesdays
Cybill Thursdays
Grace under fire fridays
Wings Saturdays
3rd Rock From The Sun Sundays

2000's:
Brothers & Sisters mondays
Two and a half men tuesdays
Desperate housewives Wednesdays
Grey's Anatomy Thursdays
Scrubs Fridays
How I Met Your Mother Saturdays
Cold Case Sundays

I can do the 1960s thru the 1990s style under each genre format by having 2 shows(in its own blocks) in 1 day

Sitcoms
Sunday: Three's Company & All in the Family
Monday: Sanford and Son & Alice
Tuesday: Happy Days & Laverne and Shirley
Wednesday: Newhart & Cheers
Thursday: ALF & Who's the Boss
Friday: One Day at a Time & WKRP in Cincinatti
Saturday: The Love Boat & Eight is Enough

Dramas
Sunday: Adam 12 & Emergency
Monday: Matlock & Remington Steele
Tuesday: Star Trek(Original) & The Twilight Zone(Original)
Wednesday: Batman & Wonder Woman
Thursday: Dynasty(Original) & The Dukes of Hazzard
Friday: Charlie Angels(Original) & Knight Rider(Original)
Saturday: China Beach & Flipper(Original)

Game Shows
Sunday: What's My Line(60s-70s) & I've Got a Secret(60s-70s)
Monday: Match Game('73-82 era) & To Tell The Truth(70s-80s)
Tuesday: Wheel of Fortune(Sajak pre-'97) & Password Plus/Super Password
Wednesday: The Price is Right(Barker 70s-80s) & Sale of the Century(80s)
Thursday: Card Sharks(Perry/Eubanks) & Family Feud(Dawson/Combs)
Friday: Love Connection(Woolery) & Pyramid(Clark 70s-80s era)
Saturday: Starcade & Double Dare('86-93 era)

I'll do decades to follow the tradition:

50s
Mondays: The Real McCoys
Tuesdays: Leave It to Beaver
Wednesdays: Bachelor Father
Thursdays: The Honeymooners
Fridays: I Love Lucy

60s:
Mondays: The Andy Griffith Show
Tuesdays: Hazel
Wednesdays: The Beverly Hillbillies
Thursdays: Petticoat Junction
Fridays: Green Acres

70s:
Mondays: Happy Days
Tuesdays: The Odd Couple
Wednesdays: Alice
Thursdays: Three's Company
Fridays: The Jeffersons

80s
Mondays: Mama's Family
Tuesdays: Gimme a Break!
Wednesdays: Amen
Thursdays: Newhart
Fridays: Designing Women

90s
Mondays: Major Dad
Tuesdays: Wings
Wednesdays: Empty Nest
Thursdays: Family Matters
Fridays: Step by Step

continuation to my post from earlier this week...

Talk Shows/Variety
Sunday: The Merv Griffin Show & Tonight Show with Jay Leno(pre-2000)
Monday: The Carol Burnett Show & Hee Haw
Tuesday: The Aresino Hall Show(original) & Nashville Now
Wednesday: Tonight Show Starring Johnny Carson & Late Night with David Letterman
Thursday: Live with Regis and Kathie Lee(pre-1999) & Soul Train(70s-80s)
Friday: ABC In Concert & Friday Night Videos
Saturday: Saturday Night Live(pre-2000) & The Midnight Special

Shows will include the whole series unless otherwise indicated. A star next to the show indicates I have not seen it but would like to.

1950s Shows
Dragnet Sundays (black and white episodes)
I Love Lucy Mondays- The lesser aired Lucy-Desi Comedy Hours would start out in the 6PM-midnight hours.
Bachelor Father and The Real McCoys* Tuesdays
Jack Benny Wednesdays
Ozzie and Harriet Thursdays
Alfred Hitchcock Fridays (Alfred Hitchcock Presents)
December Bride* and Johnny Staccato* Saturdays

1960s Dramas and Unscripted Shows
Dragnet (1967-1970) Sundays
The Alfred Hitchcock Hour Mondays
The Twilight Zone (1958-1964) Tuesdays
Route 66* Wednesdays
The Ed Sullivan Show* Thursdays
American Bandstand* Fridays
77 Sunset Strip* Saturdays

1960s Sitcoms- while Bewitched/Jeannie and The Munsters/The Addams Family would make natural pairings, I put one show from each with the other since the 2nd pairing was only 2 seasons each.
Bewitched (Dick York seasons) and The Munsters Sundays
Family Affair Mondays
The Andy Griffith Show (black and white episodes) and Gomer Pyle, U.S.M.C. Tuesdays
I Dream of Jeannie and The Addams Family Wednesdays
Petticoat Junction Thursdays
The Patty Duke Show and Leave it to Beaver Fridays
The Dick Van Dyke Show Saturdays

1970s Dramas
The Waltons Sundays (seasons 1-7)
Adam-12 (1968-1975) Mondays
Hawaii Five-O (1968-1980) Tuesdays
Eight is Enough Wednesdays
Columbo Thursdays (both 90 minute and 2 hour episodes)
The Rockford Files Fridays
Charlie's Angels (1976-1981) Saturdays

1970s Sitcoms
The Mary Tyler Moore Show Sundays
WKRP in Cincinnati Mondays
Some Mothers Do 'Ave 'Em* (aired in primetime until the series completes) and Happy Days Tuesdays
The Courtship of Eddie's Father and Mork and Mindy Wednesdays
Barney Miller Thursdays
M*A*S*H Fridays
Welcome Back, Kotter and Fawlty Towers Saturdays

1980s Dramas and Game Shows
Highway to Heaven Sundays
Lou Grant Mondays
Dick Clark Pyramid ($100,000 and $25,000) Tuesdays- would start out with seasons that have not aired on GSN.
Matlock Wednesdays
Fame Thursdays
MacGyver (1985-1994) Fridays
Remington Steele* Saturdays

1980s Sitcoms
Newhart Sundays (excluding any episodes with Prudence)
Benson Mondays
The Facts of Life and Diff'rent Strokes (no Sam + Maggie episodes) Tuesdays
Head of the Class (seasons 1-4) and What a Country* Wednesdays
Family Ties and Growing Pains Thursdays
Mr. Belvedere and The Wonder Years Fridays
Night Court (seasons 1-7) and Yes, Minister/Yes Prime Minister Saturdays

1990s Dramas
Touched by an Angel and Promised Land Sundays
7th Heaven Mondays (seasons 1-10)
Diagnosis Murder and Law and Order (Jerry Orbach episodes) Tuesdays
The X-Files (seasons 1-7) and The Practice (seasons 1-7) Wednesdays
Star Trek: the Next Generation and Star Trek: Voyager (seasons 4-7) Thursdays
Star Trek: Deep Space Nine Fridays
Early Edition Saturdays

1990s Sitcoms
Mad About You (1992-1999) and My Two Dads Sundays
Coach Mondays
Frasier and The Powers That Be* Tuesdays
Home Improvement Wednesdays
Murphy Brown (seasons 1-9) and Man of the People* Thursdays
Boy Meets World (seasons 1-5) and Sabrina the Teenage Witch (seasons 1-4) Fridays
Pacific Station* (aired in primetime until the series completes) and Wings Saturdays

2000s Shows
Gilmore Girls Sundays
Corner Gas Mondays
DAG (primetime), Hope and Faith, and Everybody Loves Raymond Tuesdays
Monk and Psych Wednesdays
Without a Trace and Beyond Belief: Fact or Fiction Thursdays
Grand Slam, Greed, and Weakest Link (Anne Robinson US) Fridays
24* (seasons 1-8) and Law and Order: Trial by Jury Saturdays

2010s Shows
Heartland (Canada) and The American Bible Challenge Sundays
Leverage, Hostages, and Granite Flats Mondays
Designated Survivor, Touch, and Timeless Tuesdays
The Middle Wednesdays
Once Upon a Time (seasons 1-4, 6), Once Upon a Time in Wonderland, and The Chase (US) Thursdays
Blue Bloods and Switched at Birth Fridays
500 Questions, Scorpion, and Outrageous 911 Saturdays

My channel would have stuff from the 50s thru the 80s on it :)

Game Shows
Big Money Mondays (Millionaire, Deal or No Deal, Greed, 1 vs. 100)
Trivia Tuesdays (Jeopardy, Trivia Trap, Blockbusters, Sale of the Century and Hollywood Squares)
Password and Wheel of Fortune Wednesdays (all versions)
Pyramid Thursdays (Clark, Davidson and Cullen)
Match Game/Family Feud Fridays (Dawson, Combs, Rayburn and Shaffer)
Shopping Saturdays (Supermarket Sweep, Let's Make a Deal and Price Is Right)
Black and White Sunday Night (What's My Line, To Tell the Truth, I've Got a Secret)

Sitcoms
Monday Night Football and Family (Coach and Family Matters)
Tim Allen Tuesdays (Home Improvement and Last Man Standing)
Boy/Girl Meets World Wednesdays
Big Bang Theory Thursdays
Full(er) House Fridays
Sabrina/Step by Step Saturdays
80s Sundays (Cosby Show, Diff'rent Strokes, ALF, Growing Pains)