for example:

back to the future-
michael j fox (marty mcfly)- Family Ties, Spin City
christopher lloyd (doc brown)- Taxi, Stacked
lea thompson (lorraine mcfly)- Caroline In The City

Jon Cryer and Charlie Sheen (Two and a Half Men)

Whoopi Goldberg (Whoopi)

Gena Davis - Commander in Chief, Sara (80's), guest starred in many shows
Sara Jessica Parker - Sex in the City (Prior - Hocus Pocus, Girls Just Wanna Have Fun, Ed Wood, HOneymoon in Vegas, etc)
Peter Boyle - Everybody Loves Raymond



Not a sitcom:
Keifer Sutherland - 24

Shirley Jones from the movie-musical Oklahoma to The Partridge Family

cheers-
ted danson- three men and a baby
kirsty alley-look who's talking
woody harrelson- white men can't jump, the larry flint story, money train, indecent proposal

also danny devito (taxi)-ruthless people, romancing the stone, throw mama from the train
robin williams (mork and mindy)- good morning vietname, mrs doubtfire, hook, one hour photo
martin lawrence (martin)- bad boys 1 and 2,
tim allen- (home improvement) wild hogs, galaxy quest