I saw them playing this in the Cheers forum and I decided to bring it here.

What you do is you look at the word in the post before yours to see what their word ends with. Then, you create another word that has to do with the show by using the last letter of one word for the beginning letter of the next word (use the subject to introduce your word). For example.

I post-
Subject: Tony's daughter is...
Message: Samantha

The next person posts-
Subject: Jonathan's mom is...
Message: Angela

Next person-
Subject: Angela is in love with...
Message: A house keeper

The last letter of the last word has to be the beginning letter of your word. Here we go with an obvious one...

Who's The Boss

(now someone post a word having to do with the show that starts with an S)

Sitcom

Mona

Angela

Anthony, the name of Angela's first kiss

(you have to go off the S)

Samantha's Growing Up
(The name of an episode)

Power play for who will say something first

Ten-o-clock
(Its time slot on Nick@Nite before the summer marathons)

Key to Angela's heart

(what Tony holds)